Among the attendees will be the Hereditary Grand Duke of Luxembourg, Prince Guillaume, the presidents of Slovakia and Bavaria, and Italian Health Minister Rannato Balduzzi.
Others notable figures will include the cardinals already in Rome. Maria Voce from the Focolare Movement and Kiko Arguello, who started of the Neocathecumenal Way.
When his last general audience ends, Benedict XVI will head to the Clementine Hall to meet with the president of the Slovak Republic, the captain regent of San Marino, the president of the Free State of Bavaria, and the co-prince of Andorra.
It will be the last formal meeting with any civilian leaders or monarchs before his resignation goes into effect at 8 pm on February 28.